The Center holds lectures for the benefit of visiting and local scholars, faculty members from the Washington area, Museum staff, and the public about the latest research in the field of Holocaust studies.

Supported by endowments since 1995, the Center organizes four annual lectures. These are the Joseph and Rebecca Meyerhoff Annual Lecture, the J.B. and Maurice C. Shapiro Annual Lecture, the Monna and Otto Weinmann Annual Lecture, and the Ina Levine Annual Lecture.